Open Question: Computer infected: Application Cannot be executed. The file wuauclt.exe is infected.?

I am not very good with computers, I do not have a clue what I’m doing, so I’m hoping I can describe my problem well enough to be able to get some help because this is making me nuts. Every 30-45 seconds I get a pop up on my screen telling me that “Application Cannot be executed. The file wuauclt.exe is infected. Do you want to activate your antivirus software now?” The first time I encountered this this problem was after something popped up saying it was doing a virus scan. When the scan popped up it asked me if I wanted delete certain things, I clicked no. Next thing I know my computer went nuts. First it’s the security warning every 30 seconds, then it pops up with something telling me to buy anti virus software from windows something rather… then on occasion it pops up with a porn site, and an ad for viagra… I don’t know what to do; the only thing functioning is the internet. I have downloaded McAfee and Super Anti-Spyware and attempted to run them in safe mode, but no dice. Please help?
Is Kaspersky compatible with Vista? The ones I’m looking at all say Windows 7.
Also, would the trial version work just as well? I just purchased McAfee to deal with this problem to no avail.

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